Molecular Formula | C23H24N2O |
Molar Mass | 344.45 |
Solubility | DMSO: ≥ 43 mg/mL |
Storage Condition | -20℃ |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.903 ml | 14.516 ml | 29.032 ml |
5 mM | 0.581 ml | 2.903 ml | 5.806 ml |
10 mM | 0.29 ml | 1.452 ml | 2.903 ml |
5 mM | 0.058 ml | 0.29 ml | 0.581 ml |
Biological activity | NSC42834 (JAK2 Inhibitor V, Z3) is an inhibitor of wild-type JAK2 and JAK2(V617F) autophosphorylation, and the IC50 range is 10-30 μM. |
target | TargetValue JAK2 (WT) () JAK2 (V617F) () |
Target | Value |